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Successful treatment of hypnic headache syndrome with flunarizine

We report nine patients with hypnic headache according to the HIS-II classificationwho were initially treated with flunarizine. Structural lesion has been rule outperforming brain MRI in all cases. In our opinion flunarizine is a very good alternativein the prophylactic treatment of hypnic headache. The efficacy of flunarizinewas moderate only in one of our patients. According to our patients evolution wethink that flunarizine is a good therapeutic option for hypnic headache, and thelow doses could be enough.


Porta-Etessam J , Muniz S , Cuadrado ML , Gonzalez-Garcia N , Orviz A , Abarrategui B , Fernandez-Matarrubia M

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