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Recurrent Guillain Barre Syndrome

Introduction: Guillain Barre Syndrome (GBS) is an acute and mix demyelinating polyneuro-radiculopathy of autoimmune cause. It produces a flaccid autoimmune paralysis. There is a consensus that the course is monophasic, nevertheless some authors have showed that it could repeat in the 3-5% of affected cases.

Case presentation: We present a case with diagnosis of GBS, who's had a similar diagnosis sixteen years ago. Spinal brain fluid study, hematologic study, hemochemistry, ionogram, gasometry, urine was done to this patient. Neurophysiologic evaluation (Motor and Sensory nerve conduction studies and F wave) also was done.

Results and Discussion: Spinal brain fluid study showed marked increase of the protein level, the rest of the laboratory studies were normal. Neurophysiologic evaluation was accordance with sensory-motor polyneuro-radiculopathy with motor predominance. We observed most abnormalities of electrophysiological parameters and proteins in spinal brain fluid in this episode in comparison with the first episode.

Conclusion: GBS recurrence is rare, but it can happen, generally there is a prolonged period of time between episodes. Symptoms and signs are similar but electrophysiological and lab parameters could be more affected in recurrent episodes.


Barbara Aymee Hernandez*, Fermin Morera Mendez and Ibis Maria Elosegui

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