Empty Sella Syndrome (ESS) is a condition where the pituitary gland is partially or totally absent from the pituitary fossa. It can be asymptomatic in most cases and found accidentally in imaging studies of brain. In symptomatic cases it presents with endocrine abnormalities due to pituitary damage visual defect from compression of optic chiasma neuropsychiatric symptoms benign intracranial hypertension CSF leakage from the nose and headache. We present a case of a 24-year-old male with psychotic symptoms, soft neurological signs with learning disabilities, empty sella syndrome, visual symptoms and cardiac valvular defect. This case helps us to understand the neuroscience behind the psychiatric illnesses having access to advanced medical technologies to look inside the brain.
Prajjita Sarma Bardoloi and Adam Abba-Aji