Myasthenia Gravis: Challenges and Therapeutics Solution

Myasthenia gravis (MG) is an autoimmune disease leading to fluctuating muscle weakness and fatigability and patients have autoantibodies against the acetylcholine receptor. MG is a postsynaptic dis¬order caused by the antibody-mediated destruction of acetyl-choline receptors (AChRs) and blockage of the binding of acetylcholine to acetylcholine receptor. Lambert-Eaton myasthenic syndrome (LEMS) is distinct autoimmune disorders that affect neuromuscular transmission. A study by Jee-Ae Kim et al. showing same clinical features and electrophysiological finding in patients of MG and LEMS

Author(s):

Sandeep Kumar Singh, Vijay Kumar and Ashok Kumar

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